Our Publications

  1. Labed SA, Wani KA, Jagadeesan S, Hakkim A, Najibi M, Irazoqui JE. Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection. Immunity. 2018; 48(5):963-978.e4. NIHMSID: NIHMS962074 PubMed [journal] PMID: 29768179, PMCID: PMC5959051

  2. Murano T, Najibi M, Paulus GLC, Adiliaghdam F, Valencia-Guerrero A, Selig M, Wang X, Jeffrey K, Xavier RJ, Lassen KG, Irazoqui JE. Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo. Scientific reports. 2017; 7(1):13938. PubMed [journal] PMID: 29066772, PMCID: PMC5655326

  3. Najibi M, Labed SA, Visvikis O, Irazoqui JE. An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense. Cell reports. 2016; 15(8):1728-42. NIHMSID: NIHMS780860 PubMed [journal] PMID: 27184844, PMCID: PMC4880541

  4. Srinivasa S, Suresh C, Mottla J, Hamarneh SR, Irazoqui JE, Frontera W, Torriani M, Stanley T, Makimura H. FNDC5 relates to skeletal muscle IGF-I and mitochondrial function and gene expression in obese men with reduced growth hormone. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 2016; 26:36-41. NIHMSID: NIHMS748441 PubMed [journal] PMID: 26774404, PMCID: PMC4716612

  5. Irazoqui JE. Why worms watch their hemidesmosomes and why you should, too. Immunity. 2015; 42(2):206-208. PubMed [journal] PMID: 25692695

  6. Hamarneh SR, Murphy CA, Shih CW, Frontera W, Torriani M, Irazoqui JE, Makimura H. Relationship between serum IGF-1 and skeletal muscle IGF-1 mRNA expression to phosphocreatine recovery after exercise in obese men with reduced GH. The Journal of clinical endocrinology and metabolism. 2015; 100(2):617-25. PubMed [journal] PMID: 25375982, PMCID: PMC4318910

  7. Irazoqui JE. DAF-tly depart stinky situations with elegans. Cell host & microbe. 2014; 16(5):553-5. PubMed [journal] PMID: 25525785

  8. Visvikis O, Ihuegbu N, Labed SA, Luhachack LG, Alves AF, Wollenberg AC, Stuart LM, Stormo GD, Irazoqui JE. Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes. Immunity. 2014; 40(6):896-909. NIHMSID: NIHMS598830 PubMed [journal] PMID: 24882217, PMCID: PMC4104614

  9. Settembre C, De Cegli R, Mansueto G, Saha PK, Vetrini F, Visvikis O, Huynh T, Carissimo A, Palmer D, Klisch TJ, Wollenberg AC, Di Bernardo D, Chan L, Irazoqui JE, Ballabio A. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop. Nature cell biology. 2013; 15(6):647-58. NIHMSID: NIHMS477636 PubMed [journal] PMID: 23604321, PMCID: PMC3699877

  10. Lapierre LR, De Magalhaes Filho CD, McQuary PR, Chu CC, Visvikis O, Chang JT, Gelino S, Ong B, Davis AE, Irazoqui JE, Dillin A, Hansen M. The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans. Nature communications. 2013; 4:2267. NIHMSID: NIHMS534805 PubMed [journal] PMID: 23925298, PMCID: PMC3866206

  11. Brown S, Xia G, Luhachack LG, Campbell J, Meredith TC, Chen C, Winstel V, Gekeler C, Irazoqui JE, Peschel A, Walker S. Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109(46):18909-14. PubMed [journal] PMID: 23027967, PMCID: PMC3503181

  12. Luhachack LG, Visvikis O, Wollenberg AC, Lacy-Hulbert A, Stuart LM, Irazoqui JE. EGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathways. PLoS pathogens. 2012; 8(7):e1002798. PubMed [journal] PMID: 22792069, PMCID: PMC3390412

  13. Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE. An image analysis toolbox for high-throughput C. elegans assays. Nature methods. 2012; 9(7):714-6. NIHMSID: NIHMS397906 PubMed [journal] PMID: 22522656, PMCID: PMC3433711

  14. Irazoqui JE. Transparent worms help survey the fortress of innate immunity. Virulence. 2011; 2(2):83-5. PubMed [journal] PMID: 21460640

  15. Irazoqui JE, Troemel ER, Feinbaum RL, Luhachack LG, Cezairliyan BO, Ausubel FM. Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. PLoS pathogens. 2010; 6:e1000982. PubMed [journal] PMID: 20617181, PMCID: PMC2895663

  16. Irazoqui JE, Ausubel FM. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis. Clinical and experimental immunology. 2010; 160(1):48-57. PubMed [journal] PMID: 20415851, PMCID: PMC2841835

  17. Irazoqui JE, Urbach JM, Ausubel FM. Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nature reviews. Immunology. 2010; 10(1):47-58. NIHMSID: NIHMS228660 PubMed [journal] PMID: 20029447, PMCID: PMC2965059

  18. Irazoqui JE, Ng A, Xavier RJ, Ausubel FM. Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. Proceedings of the National Academy of Sciences of the United States of America. 2008; 105(45):17469-74. PubMed [journal] PMID: 18981407, PMCID: PMC2582251

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